Abstract: In recent years, Interent of Things had attracted wide attention around the world. An indoor environmental monitoring system is designed under framework of Interent of Things. The system is accomplished based on wireless sensor network and virtual instrument. The monitoring platform receives data from wireless sensors and communicates with a server through a local area network. The server displays real-time monitoring results and controlls external equipment with the aid of the monitoring platform. The wireless sensor nodes adoptes TinyOS, and the communication program of nodes is compiled in NesC. Based on virtual instrument, a man-machine interactive program is desgined in LabVIEW.