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XIA Du-ling, LI Xue-fang. Determination of Amlodipine Maleate in Tablet by Differential Spectrophotometry[J]. Journal of University of Electronic Science and Technology of China, 2008, 37(3): 464-465,473.
Citation: XIA Du-ling, LI Xue-fang. Determination of Amlodipine Maleate in Tablet by Differential Spectrophotometry[J]. Journal of University of Electronic Science and Technology of China, 2008, 37(3): 464-465,473.
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Determination of Amlodipine Maleate in Tablet by Differential Spectrophotometry

  • 1.

    School of Microeletronics and Solid-State Electronics,University of Electronic Science and Technology of China Chengdu 610054

  • Received Date: 2006-12-08
  • Rev Recd Date: 2007-08-30
  • Publish Date: 2008-06-15
  • Amlodipine maleate is a new kind of medicine for hypertensive disease. This article mainly studies the conditions of quantitatively measuring amlodipine maleate of tablet. The double-wave, 365 nm and 425 nm, spectrophotometry was used for determining the content of the amlodipine maleate tablet to eliminate interference of excipient. The absorbance is well linear with concentration between 5.0 μg/ml and 50.0 μg/ml, and the linear equation of differential spectrophotometry is △A=0.01149C+0.003 (r=0.9994), the coefficient of recovery is 99.92%, and RSD is 0.67%.
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Determination of Amlodipine Maleate in Tablet by Differential Spectrophotometry

  • 1. School of Microeletronics and Solid-State Electronics,University of Electronic Science and Technology of China Chengdu 610054
  • Received Date: 2006-12-08
  • Rev Recd Date: 2007-08-30
  • Publish Date: 2008-06-15

Abstract: Amlodipine maleate is a new kind of medicine for hypertensive disease. This article mainly studies the conditions of quantitatively measuring amlodipine maleate of tablet. The double-wave, 365 nm and 425 nm, spectrophotometry was used for determining the content of the amlodipine maleate tablet to eliminate interference of excipient. The absorbance is well linear with concentration between 5.0 μg/ml and 50.0 μg/ml, and the linear equation of differential spectrophotometry is △A=0.01149C+0.003 (r=0.9994), the coefficient of recovery is 99.92%, and RSD is 0.67%.

XIA Du-ling, LI Xue-fang. Determination of Amlodipine Maleate in Tablet by Differential Spectrophotometry[J]. Journal of University of Electronic Science and Technology of China, 2008, 37(3): 464-465,473.
Citation: XIA Du-ling, LI Xue-fang. Determination of Amlodipine Maleate in Tablet by Differential Spectrophotometry[J]. Journal of University of Electronic Science and Technology of China, 2008, 37(3): 464-465,473.
shu

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