Abstract: In the era of information explosion, online social network has been widely depended and applied as the main way of information transmission. However, the dynamic process of information transmission is often difficult to accurately predict and prevent in online social network. In this paper, the hyperedges in hypergraphs are introduced to describe complex social relationships between two or more individuals. Based on the hypernetwork dynamic evolution model, we construct online social hypernetwork, and combine with the susceptible infected susceptible (SIS) model based on the reaction process strategy, the theoretical analysis and simulation of the dynamic process of global information dissemination in the online social hypernetwork are carried out. The analytical expressions between structure parameters of the hypernetwork, spreading rate and recovering rate are obtained by using the mean field theory. And then we discuss the impact of parameters including the hypernetwork scale, spreading rate, recovering rate, structure parameters of the hypernetwork as well as initial spreading nodes on the global dissemination of information. Further, a comparative analysis of the process of global information dissemination under the hypernetwork and complex network structure is carried out. The results of the study are helpful for a deeper understanding of the dissemination laws and development trends of global dissemination of information in online social network, and provide scientific basis for practical applications such as information detection and public opinion control.