Abstract: In order to study the influence of electromagnetic (EM) transients on the structural design of test breeder module (TBM), two plasma major disruptions in ITER and the physical environment of Chinese solid breeder TBM for EM field analysis are simulated by ANSYS finite element software. The eddy currents induced by EM transients and the trend of Lorentz forces caused by the interactions of magnetic field and the eddy currents are evaluated. Meanwhile, the structure stress, displacement of deformation, and the Joule heating effect caused by eddy currents on TBM are obtained by coupling calculation of multi-physical field. The results show that the maximum equivalent stresses and the temperature rises produced by the linear and exponent disruption are satisfied with the requirements of safety design. Moreover, the sensitivity analysis indicates that the maximum equivalent stress can be reduced by changing the length of cartridge, which provides reference for safety design of TBM.