Abstract: On the basis of parallelizable real-time motion tracking algorithm, we propose the modified weighted phase separation (WPS) displacement estimation algorithm based on lateral guidance and 2D estimation window, and validate whether this algorithm can improve elastography performance. The displacement of the middle A-lines is estimated as the seed displacement, the other displacements are estimated from the middle to two sides, their initial displacements are selected from the lateral adjacent displacement estimate, and the final displacements are generated by using 2D weighted phase separation algorithm. The simulation shows that the modified WPS algorithm can achieve elastogram with higher SNRe than the original WPS at various strains or window-lengths. And the phantom experiment also shows that the modified WPS algorithm can generate the higher performance elastogram.