Abstract: To the single-chip microcomputer that used for the production field is general with were tested the object distance farther, easily suffer the assault of every kind of interference。this will require the single-chip microcomputer system to have very high and dependable, make it can resist the assault of every kind of interference.Therefore, anti-interference design is the applied system importantly constitute part.This is according to the circumstance of the actual production field, to discussed the inner part of the apply system with the exterior's interference source、analog channel's interference and solution、switch channel's interference and solution;the power system's interference and solution.And to because the interference result in of" die machine" appearance bring upped soft solution scheme.