Abstract: In this study, the transfer entropy method is used to investigate the neural network effects on brain functional abnormalities in individuals with antisocial behavior (ASB). The results reveal a significant decrease in global synchronization properties within the ASB group, and most importantly, significant regional differences in nodal betweenness and nodal degree centrality. Particularly, individuals with ASB exhibit a significant decrease in nodal betweenness centrality in the right temporal lobe, left occipital lobe, and fusiform, coupled with a significant increase in the left inferior frontal gyrus, insula, and precuneus. Alterations in nodal degree centrality manifest a decrease in regions such as the right middle to medial frontal gyrus and superior occipital lobe, alongside an increase in regions such as the bilateral posterior central gyrus, left inferior temporal gyrus, and insula. Furthermore, the ASB group displays significantly different connectivity patterns across 14 typical brain networks. These findings provide important insights for understanding the neural basis of antisocial behavior.