Abstract: This paper proposes an Electronic Commerce (EC) system frame based on grid and multi-agent negotiation strategy. Resources and users can be reasonably organized and managed, thus information isolated island can be eliminated and searching efficiency can be improved. This paper employ Broke Agent (BA) to control transaction process. BA collects real-time information and provider parameters referenced in negotiation. ABuyer and AProvider are used to represent buyer and provider respectively and realize independent negotiation. Flexible and self-adaptive negotiation strategies are designed to improve performance and efficiency of negotiation.