Abstract: PCI interface connection between Motorola PowerPC 860 MPU system and PC host is complemented using PLX 9050 chip based on Windows 2000.A solution of interconnection between MPU and computer system by means of PCI interface is given. Our discussion centre on the basic method and procedure of developing PCI interface device driver on Windows 2000 system in this paper. This approach can further be applied to develop CompactPCI interface device driver and provides us a convenient and fast way to program for PC in industrial control applications.