Abstract: Materials genome is an emerging technology to accelerate materials discovery, development, and deployment. In the past two decades, high-throughput materials experimentation tools have been developed and applied successfully to the discovery of a number of materials, ranging from advanced catalysts, dielectrics, electrodes, to high-temperature alloys. Materials computation and database technologies have also made remarkable progresses, particularly represented by the integrated computational materials engineering (ICME) developed in the past decade. Materials genome research integrates high-throughput computation and simulation, high-throughput experimentation, and materials database, throughout the materials discovery-to-deployment process, targeting to cut the materials development time and cost significantly. This review, is trying to give a brief and comprehensive introduction to materials genome technologies, with emphasis on high-throughput materials experimentation, as well as applications of materials computation and database. University of Electronics Science and Technology of China is one of the most active institutes in China in the filed of materials genome research, and some progresses are also highlighted in this review.