Abstract: Impedance matching technology is the key to designing high-frequency electronic circuits. In order to solve the problem of impedance matching of transmission lines with special structures, the basic characteristics of the transmission line with multi-branch structure are studied based on the principle of impedance matching of transmission lines, and signal transmission characteristics of transmission line with multi-branch structure are analyzed in depth. Combined with the zero-order model of transmission line, the impedance matching conditions of multi-branch structure are obtained, and the simulation results are given. This paper summarizes the main factors influencing the signal characteristics in the model. As well, it further optimizes the solution to the impedance matching of the transmission line with multi-branch structure.